Intermediates-Anticancer

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Product

No.	PRODUCTS	INTERMEDIATE	STRUCTURE	CAS No.
1	Ibrutinib	3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine		330786-24-8
2	Elacestrant	7-(benzyloxy)-3-bromo-1,2-dihydronaphthalene		722536-73-4
		N-(2-bromo-5-methoxyphenyl)acetamide		123027-99-6
		N-ethyl-2-(4-formylphenyl)acetamide		2477812-42-1
		N-(2-(6-(benzyloxy)-3,4-dihydronaphthalen-2-yl)-5-methoxyphenyl)acetamide		2477812-37-4
3	Relugolix	3-amino-6-methoxypyrid azine		7252-84-8
		2-((2,6-difluorobenzyl)(ethoxycarbonyl)amino)-4- ((dimethylamino)methyl) -5-(4-nitrophenyl)thiophe ne-3-carboxylic acid		1589503-95-6
		Ethyl 2-((2,6-difluorobenzyl)(ethoxycarbonyl)amino)-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate		308831-94-9
		Ethyl 5-(4-aminophenyl)-2-((2,6-difluorobenzyl)propoxycarbonyl) amino)-4-((dimethylamino)methyl)thiophene-3-carboxylate		N/A
		1-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-3-methoxyurea		737789-87-6
4	Aprepitant	(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol		127852-28-2
4	Aprepitant	(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride		171482-05-6
5	Ruxolitinib	4-(1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine		941685-27-4
6	Venetoclax	2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid		1235865-77-6
		1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine hydrochloride		1228780-72-0
		Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate		1235865-75-4
7	Niraparib	Methyl 3-formyl-2-nitrobenzoate		138229-59-1
7	Niraparib	Tert-butyl (S)-3-(4-aminophenyl)piperidine-1-carboxylate		1171197-20-8
8	Palbociclib	6-bromo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one		1016636-76-2
8	Palbociclib	1-BOC-4-（6-aminopyridin-3-yl）piperazine		571188-59-5
9	Nintedanib	N-(4-Aminophenyl)-N,4-Dimeth yl-1-Piperazineacetamide		262368-30-9
		Methyl 2-Oxoindole-6-Carboxylate		14192-26-8
		(3E)-2,3-Dihydro-3-(MethoxyPhenylMethylene)-2-Oxo-1H-Indole-6-Carboxylic Acid Methyl Ester		1168150-46-6
10	Tucatinib	2-Chloro-5-nitrotoluene		13290-74-9
		2-Fluor-5-nitrotoluol		455-88-9
		[1,2,4]Triazolo[1,5-a]pyridin-7-ol		1033810-70-6
11	Linperlisib	3-amino-2-methoxypyridine-5-boronic acid pinacol ester		893440-50-1

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